Spurs were second best for much of the encounter and conceded first, but after equalising and then holding firm against a dominant Arsenal, Alderweireld glanced home late on to move Jose Mourinho's men above the Gunners in the table.
The match burst into life with Lacazette's goal – the Frenchman blasting into the top-left corner after Granit Xhaka had won possession back from Serge Aurier.
However, Arsenal's lead lasted just 137 seconds, defensive concentration proving their Achilles heel yet again as Sead Kolasinac's mishit pass to David Luiz released Son, who provided a clever finish over the approaching Emiliano Martinez.
Arsenal's goalkeeper did make a decisive intervention just past the half-hour mark, though, tipping Ben Davies' piledriver onto the bar, before an Aubameyang free-kick went agonisingly wide at the other end.
